High Risk Pregnancy Pregnant women under 17 or over 35 are considered high-risk pregnancies. Being pregnant with multiple babies. Having a history of complicated pregnancies, such as preterm labor, C-section, pregnancy loss or having a child with a birth defect. A family history of genetic conditions.. Medical conditions that exist before pregnancy. Conditions that can pose risks to the mother or baby include: High blood pressure Lung, kidney, or heart problems Diabetes